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Question: Using a Punnett square, work out the distribution of phenotypic features in the first filial generation after a cross between a homozygous female and a heterozygous male for a single locus.

Answer:

In guinea pigs, heterozygous male with black coat colour (Bb) is crossed with the female having white coat colour (bb). The male will produce two types of gametes, B and b, while the female will produce only one kind of gamete, b. The genotypic and phenotypic ratio in the progenies of F1 generation will be same i.e., 1:1.

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