Gene therapy is an attempt to correct a | Class 12 Biology Chapter Biotechnology and its Application, Biotechnology and its Application NCERT Solutions

Question:

Gene therapy is an attempt to correct a genetic defect by providing a normal gene into the individual. By this the normal function can be restored. An alternate method would be to provide the gene product (protein/enzyme) known as enzyme replacement therapy, which would also restore the function. Which in your opinion is a better option? Give reason for your answer.

Answer:

Gene therapy is a technique for correcting the defective genes responsible for disease development. It typically aims to supplement a defective mutant allele with a functional one. Several approaches have been given for correcting defective or abnormal genes like gene addition, gene replacement, and abnormal gene can be repaired through selective reverse mutation, which returns the gene to its normal function. And mainly it involves the germ line gene therapy which involves the permanent transmissible modifications of the genome of a gamete, a zygote or an embryo. Gene therapy is considered to be better option than enzyme replacement therapy because it has potential to for the complete cure of the gene defect.     


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Welcome to the NCERT Solutions for Class 12 Biology - Chapter . This page offers a step-by-step solution to the specific question from Excercise 0 , Question 12: Gene therapy is an attempt to correct a genetic defect by providing a normal gene into the individua....