With respect to understanding diseases, | Class 12 Biology Chapter Biotechnology and its Application, Biotechnology and its Application NCERT Solutions

Genetic manipulation of animal cells or animals that have been permanently engineered by the gene insertion are known as transgenic animals and these contains functional foreign genes that have been introduced into the genome by genetic engineering. These transgenic are designed to increase study of how genes contribute to development of diseases and these are made to serve as the models for the human diseases like cancer, cystic fibrosis, Alzheimer etc. so that preventive measures are taken. For example: Transgenic Goats, they have human gene which codes for blood clot dissolving protein, i.e. Tissue plasminogen activator (TPA) is formed, secreted in milk. And, this is used for the treatment of coronary thrombosis disease.