What would happen if histones were to be mutated and made rich in acidic amino acids such as aspartic acid and glutamic acid in place of basic amino acids such as lysine and arginine?
If histones were mutated and made rich in acidic amino acids. They will not be able to keep the DNA coiled around them because DNA is negatively charged molecule and histones are positively charged due to basic amino acids. That is how, are attracted to each other. If histones become negatively charges, instead of binding, they will rather repel DNA. The packaging of DNA in eukaryotes would not happen. Therefore, the chromatin fibre would not be formed.
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Welcome to the NCERT Solutions for Class 12 Biology - Chapter . This page offers a step-by-step solution to the specific question from Excercise 0 , Question 9: What would happen if histones were to be mutated and made rich in acidic amino acids such as asparti....
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