How is a mature, functional insulin horm | Class 12 Biology Chapter Biotechnology and its Application, Biotechnology and its Application NCERT Solutions

Question:

How is a mature, functional insulin hormone different from its prohormone form?

Answer:

Insulin is a polypeptide hormone that is used for saving the diabetic patients due to failure of insulin secretion in the pancreas or when the patient have low glucose level/ low blood sugar level then insulin injection is given and is composed of 51 amino acids arranged in two chains that are linked together by two disulfide bridges. It is produced by the β- cells of the islets of Langerhans and it favors the synthesis of glycogen, triacylglycerols and proteins. This acts to reduce the glucose concentration in the blood and thus stimulates the conversion of glucose to fats, proteins, ribulose 5- phosphate and glycogen etc.

Mature insulin is obtained by processing the pro- hormone that contains extra peptide known as C- peptide. Then, the C- peptide stretch of chain is removed during the conversion of prohormone to mature hormone (maturation process).


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Welcome to the NCERT Solutions for Class 12 Biology - Chapter . This page offers a step-by-step solution to the specific question from Excercise 0 , Question 11: How is a mature, functional insulin hormone different from its prohormone form?....