Name a few enzymes involved in DNA repli | Class 12 Biology Chapter Molecular Basis of Inheritance, Molecular Basis of Inheritance NCERT Solutions

The process of making identical or same copies of dsDNA (double stranded DNA) by using template DNA or existing DNA for the synthesis of new strand is known as DNA replication. Many enzymes and proteins are involved in this process:

1. DNA helicase and primase: These are the two enzymes that enables the polymerase to work on a duplex DNA. DNA helicase opens the duplex helix at the replication fork which provides single strand as an template. Primase synthesizes a short RNA primers which leads to DNA chain elongation.
2. Topoisomerase: These are required to relieve or for the removal of positive supercoiling of DNA which arises by the DNA unwinding and DNA gyrase has that ability to remove that supercoiling and introduces negative supercoiling to the DNA.