What are recombinant DNA vaccines? Give | Class 12 Biology Chapter Human Health and Disease, Human Health and Disease NCERT Solutions

Question:

What are recombinant DNA vaccines? Give two examples of such vaccines. Discuss their advantages.

Answer:

Recombinant vaccines are made up of a small circular DNA (plasmid) that has very tiny piece of pathogen DNA incorporated in it to produce one or two specific proteins of the pathogen.

This recombinant DNA is introduced in to the bacteria or yeast cells, where it can use cell’s machinery to produce polypeptides of the pathogen. These are used as vaccine to trigger a range of immune responses. Vaccine produced by using this approach allow large scale production, e.g.

  1. Hepatitis- B vaccine produced from yeast
  2. Bird flu DNA vaccine

Advantages:

  1. Recombinant DNA vaccines are advantageous over killed or attenuated vaccines since they does not get virulent or mutated again as it is seen in case of attenuated vaccines.
  2. Secondly, these are highly pure, specific and elicits strong immune response.


Study Tips for Answering NCERT Questions:

NCERT questions are designed to test your understanding of the concepts and theories discussed in the chapter. Here are some tips to help you answer NCERT questions effectively:

  • Read the question carefully and focus on the core concept being asked.
  • Reference examples and data from the chapter when answering questions about Human Health and Disease.
  • Review previous year question papers to get an idea of how such questions may be framed in exams.
  • Practice answering questions within the time limit to improve your speed and accuracy.
  • Discuss your answers with your teachers or peers to get feedback and improve your understanding.

Comments

Comment(s) on this Question

Welcome to the NCERT Solutions for Class 12 Biology - Chapter . This page offers a step-by-step solution to the specific question from Excercise 0 , Question 8: What are recombinant DNA vaccines? Give two examples of such vaccines. Discuss their advantages....