A single base mutation in a gene may not | Class 12 Biology Chapter Molecular Basis of Inheritance, Molecular Basis of Inheritance NCERT Solutions

Question:

A single base mutation in a gene may not ‘always’ result in loss or gain of function. Do you think the statement is correct? Defend your answer.

Answer:

The statement is correct. Because of degeneracy of codons, mutation at third base of codon, usually does not result into any change is phenotype. This is called silent mutations.

On the other hand, if codon is changed in any way that now it specifies another amino acid, it may do other protein functions as it happens in case of β- globulin of haemoglobin protein. Whereas substitution of valine instead of glutamic acid causes change in its structure and function and resulting into sickle cell trait.  


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Welcome to the NCERT Solutions for Class 12 Biology - Chapter . This page offers a step-by-step solution to the specific question from Excercise 0 , Question 13: A single base mutation in a gene may not ‘always’ result in loss or gain of function. Do....